C Diff Kills, it’s Curable, it’s Avoidable
Posted in Newest drugs on Mar 13th, 2009
There are multiple strains of C Diff floating around our hospitals and this one is pretty scary. “This NAP1 strain has a genetic change that results in literally 16 to 23 times more toxin,” says William Jarvis, MD according to an excellent recent College of American Pathologists article [1]. In the same article, L. Clifford [...]
Posted in Newest drugs on Feb 19th, 2009
It looks like “Fidaxomicin (formerly OPT-80, PAR-101 or Difimicin),” is still looking very promising so be sure to keep searching for its new name, Fidaxomicin. [1] Again, Fidaxomicin is a new drug soon to complete its last studies before applying for FDA approval. It has been shown, so far, to a tiny bit more effective [...]
Posted in Newest drugs on Nov 26th, 2008
According to TheStreet.com [1], top-line results of Optimer’s phase III Opt-80 study are demonstrating higher cure rates and lower relapse rates when compared to vancomycin.
Cure Rates Similar
If you ask me, the cure rates were similar (88% versus 86%), but this is still fantastic news. Currently, there are two antibiotics being widely used to treat C [...]
Posted in Newest drugs on Nov 9th, 2008
This drug is looking promising to me and it is getting much closer to being available. The FDA has granted this drug Fast-Track status. According to a great pdf from the maker of the drug, the company estimates that its second (and I think final) trial will complete in 2009.[1] After that the FDA/EAMA begin [...]
Posted in Newest drugs on Apr 12th, 2008
OPT-80 (or “PAR-101″ or “Difimicin”)
According to PipelineReview.com and Optimer Pharmaceuticals, there may be a new drug coming out that “may eradicate C. difficile selectively,” [1] which could be a huge breakthrough in the treatment of Clostridium Difficile infections.
This drug is fantastic news for people suffering from multiple relapses.
The makers of the new drug say: [...]